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IRTG / Soft Matter Science
Freiburger Materialforschungszentrum
Stefan-Meier-Str. 21
79104 Freiburg, Germany

Contact: Jana Husse

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softmattergraduate[at]uni-freiburg.de


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You are here: Home Events Prof. Dr. Andreas Janshoff "Cell Mechanics: How the Plasma Membrane/Cortex Interface Withstands External Forces"

Prof. Dr. Andreas Janshoff "Cell Mechanics: How the Plasma Membrane/Cortex Interface Withstands External Forces"

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Institute of Physical Chemistry University of Göttingen, Germany

What
  • Seminar
When Apr 20, 2016
from 02:15 PM to 03:00 PM
Where Seminarraum A, FMF, Stefan-Meier-Str. 21, Freiburg
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Plasma membrane tension is responsible for a variety of cellular functions such as motility, cell division, and endocytosis. Besides, cellular mechanics is generally impacted by membrane mechanics in conjunction with the actomyosin cortex. A model is proposed the captures the essential physics of composite shells under prestress. Since membrane tension is dominated by the attachment of the actin cortex to the inner leaflet of the plasma membrane, we investigated the importance of ezrin, a major cross-linker of the membrane-cytoskeleton interface, for cellular mechanics of confluent MDCK II cells. We try to provide a comprehensive picture of cellular mechanics by using also bottom-up approaches that model the essential feature of cellular membranes.

 

invited by Winfried Römer

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