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Freiburger Materialforschungszentrum
Stefan-Meier-Str. 21
79104 Freiburg, Germany

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You are here: Home Events Dr. Ewelina Burakowska-Meise "UPy-based supramolecular polymers - a modular approach to biospecific materials"

Dr. Ewelina Burakowska-Meise "UPy-based supramolecular polymers - a modular approach to biospecific materials"

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Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands

What
  • Seminar
When Feb 10, 2011
from 02:15 PM to 03:00 PM
Where “Hörsaal Makromolekulare Chemie”, Stefan-Meier-Str. 31, Freiburg
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Abstract

Supramolecular materials have been shown to be suitable for a variety of different purposes, including many biomedical applications. In particular, biodegradable prepolymers modified with the quadruple hydrogen-bonding ureido-pyrimidinone (UPy) unit, combine easy processing (e.g. melt processing at relatively low temperatures), tunable mechanical performance (e.g. strength), and tunable degradation behavior, which can be exploited in various ways.

Here, I will discuss the possibilities of using the UPy-based supramolecular polymers as permanent/temporary scaffold in tissue engineering. Preliminary results show a strong correlation between various UPy-based functionalized peptides and cell adhesion properties. Furthermore, I will present our current research towards identifying and evaluating appropriate materials for biomedical applications. Finally, I will discuss the relationship between polymer surface structure and cell activity.

 

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