Dr. Ewelina Burakowska-Meise "UPy-based supramolecular polymers - a modular approach to biospecific materials"
Department of Biomedical Engineering, Eindhoven University of Technology, The Netherlands
What |
|
---|---|
When |
Feb 10, 2011 from 02:15 PM to 03:00 PM |
Where | “Hörsaal Makromolekulare Chemie”, Stefan-Meier-Str. 31, Freiburg |
Add event to calendar |
vCal iCal |
Abstract
Supramolecular materials have been shown to be suitable for a variety of different purposes, including many biomedical applications. In particular, biodegradable prepolymers modified with the quadruple hydrogen-bonding ureido-pyrimidinone (UPy) unit, combine easy processing (e.g. melt processing at relatively low temperatures), tunable mechanical performance (e.g. strength), and tunable degradation behavior, which can be exploited in various ways.
Here, I will discuss the possibilities of using the UPy-based supramolecular polymers as permanent/temporary scaffold in tissue engineering. Preliminary results show a strong correlation between various UPy-based functionalized peptides and cell adhesion properties. Furthermore, I will present our current research towards identifying and evaluating appropriate materials for biomedical applications. Finally, I will discuss the relationship between polymer surface structure and cell activity.